![]() ![]() 15.0-25.0 mEq/L – Altered atrioventricular conduction and (further) complete heart block.10.0-13.0 mEq/L – Respiratory depression.7.0–10.0 mEq/L – Loss of patellar reflex.As per Lu and Nightingale, serum magnesium concentrations associated with maternal toxicity (also neonate depression, hypotonia and low Apgar scores) are: The therapeutic range for the prevention of the pre-eclamptic uterine contractions is: 4.0–7.0 mEq/L. >5.0 mEq/L – Prolonged atrioventricular conduction.Magnesium acts as a physiologic calcium blocker, which results in abnormalities of the electrical conduction system of the heart.Ĭonsequences related to serum concentration: As well as nausea, low blood pressure, low blood calcium, abnormal heart rhythms and asystole, dizziness, and sleepiness.Ībnormal heart rhythms and asystole are possible complications of hypermagnesemia related to the heart. Symptoms include weakness, confusion, decreased breathing rate, and decreased reflexes. Rates among hospitalized patients in renal failure may be as high as 10%. Treatment when levels are very high include calcium chloride, intravenous normal saline with furosemide, and hemodialysis. Treatment involves stopping the magnesium a person is getting. Specific electrocardiogram (ECG) changes may be present. It is severe if levels are greater than 2.9 mmol/L (7 mg/dL). Diagnosis is based on a blood level of magnesium greater than 1.1 mmol/L (2.6 mg/dL). Less common causes include tumor lysis syndrome, seizures, and prolonged ischemia. It is typically caused by kidney failure or is treatment-induced such as from antacids that contain magnesium. Complications may include low blood pressure and cardiac arrest. Hypermagnesemia is an electrolyte disorder in which there is a high level of magnesium in the blood. Kidney failure, high blood calcium, high blood potassium, hypoparathyroidism, hypothyroidism, lithium toxicity, red blood cell breakdown, rhabdomyolysis Ĭalcium chloride, intravenous normal saline with furosemide, hemodialysis Kidney failure, treatment induced, tumor lysis syndrome, seizures, prolonged ischemia īlood level > 1.1 mmol/L (2.6 mg/dL) Weakness, confusion, decreased breathing rate
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